Philips Avent SCF421/27 Anti-colic baby bottle Newborn Nipple lets nursing newborns control the flow of milk like with breastfeeding, which can reduce spit-up and overeating. Philips Avent's anti-colic valve flexes to keep air in the bottle and out of your baby's tummy, a feature that reduces fussing and colic. In a clinical trial, two-week-old infants fed with a Philips Avent Anti-colic baby bottle bottle experienced less colic than babies fed with a conventional bottle, with the greatest difference seen at night. The Newborn Nipple has a single hole, so newborns can learn to eat with the slowest flow Philips Avent offers. The nipple is made of flavorless, odorless silicone that resists discoloring and stickiness. The nipple's soft, rounded shape promotes feeding for babies who nurse from both the breast and a bottle. The Anti-colic baby bottle BPA Free nipples are dishwasher safe and can be sterilized by boiling for five minutes or by using a Philips Avent steam sterilizer.